AUTOLOGOUS STEM-CELL TRANSPLANTATION AS CONSOLIDATION OF FIRST-LINE CHEMOTHERAPY IN PATIENTS WITH PERIPHERAL T-CELL LYMPHOMA: A MULTICENTER GELTAMO/FIL STUDY

Peripheral T-cell lymphomas (PTCL) are a heterogeneous group of rare lymphoid malignancies that mostly have poor prognoses with currently available treatments.Upfront consolidation with autologous stem cell transplantation (ASCT) is frequently carried out, but its efficacy has never been investigated in randomized trials.We designed a multicenter,

The Trans-Atlantic Slave Trade, which occurred between the fifteenth and nineteenth centuries, displaced Africans and people of African descent into the New World.The trade affected and influenced several aspects of the world economy, boosting the economies of participating countries and creating what would become the African diaspora.While several

Nearly 50,000 Canadian children live in foster care.Compared with their peers, foster children experience greater independence and decreased guidance, predisposing them to harmful exposures such as traumatic brain injury (TBI), illicit drugs, and alcohol.Foster children also report a higher level of childhood abuse compared with the general populat

Cellular homeostasis is essential for the physiology of eukaryotic cells.Eukaryotic cells, including plant cells, utilize two main pathways to adjust dosatron d40mz2 the level of cytoplasmic components, namely the proteasomal and the lysosomal/vacuolar pathways.Macroautophagy is a lysosomal/vacuolar pathway which, until recently, was thought to be

During the Coronavirus (COVID-19) pandemic, in-person interpreters have been deemed ?nonessential,? and thus eliminated to minimize viral exposure and conserve personal protective ultra violette lip balm equipment.Considering alarming patterns of interpreter underuse, we evaluate how substitution for remote modalities (telephone or video) may exace